How to Be Molecular Pathology Technologist - Job Description, Skills, and Interview Questions

Jul 30, 2020 / 6 Minutes Read / By Albert

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Molecular Pathology Technologists play a vital role in the diagnosis and treatment of diseases. By studying and analyzing the molecular structure of cells, they are able to detect changes at the DNA level and uncover the cause of a disease. These findings can then be used to create a personalized treatment plan that targets the specific molecular cause of the disease.

Molecular Pathology Technologists are essential in developing better diagnostic tests and new treatments for diseases, as they are able to identify changes in cells and DNA that can be used to target specific treatments. As a result, this helps to improve patient outcomes and reduce the cost of healthcare.

Steps How to Become

Obtain a high school diploma or equivalent. In order to become a molecular pathology technologist, it is necessary to have a high school diploma or equivalent. High school coursework in science, math and biology can be beneficial for those interested in this field.
Enroll in a post-secondary program. Many post-secondary schools offer certificate and degree programs in molecular pathology technology. These programs typically include coursework in medical terminology, anatomy, physiology, clinical chemistry, clinical microbiology and molecular biology.
Complete an internship. Many programs require students to complete an internship or practicum in an approved clinical setting. During the internship, students will gain hands-on experience in molecular pathology technology under the guidance of an experienced supervisor.
Earn certification. After completing a program and internship, technologists may choose to pursue voluntary certification. The American Society for Clinical Pathology offers certification in molecular pathology technology. Certification can demonstrate a level of expertise and increase employment opportunities.
Find employment. Molecular pathology technologists may find employment in research laboratories, hospitals and diagnostic clinics. Technologists may also choose to specialize in a certain area of pathology, such as genetic testing or cancer diagnostics.

Molecular Pathology Technologist is a highly specialized position that requires extensive knowledge and experience in the fields of molecular biology and genetics. To be ideal and qualified for this role, the individual must be highly skilled in the setup, operation, and troubleshooting of laboratory equipment; possess an advanced understanding of molecular biology and genetic testing procedures; and have an excellent attention to detail. A successful Molecular Pathology Technologist should also have strong organizational skills and be able to effectively communicate with colleagues, clients, and other stakeholders.

Furthermore, they should have the ability to analyse complex data accurately and make informed decisions. All of these qualities combined will ensure that the individual is fully equipped to excel in this challenging yet rewarding role.

You may want to check Embedding Technician, Histology Lab Manager, and Immunoassay Technologist for alternative.

Job Description

Perform molecular genetic testing, including amplification techniques such as PCR, RT-PCR and Southern Blot.
Analyze and interpret results of molecular tests, and communicate findings to physicians.
Perform laboratory maintenance, including ordering and stocking reagents, supplies, and equipment.
Design, develop, validate, and utilize new and existing molecular techniques.
Prepare specimens for transport to external laboratories for specialized testing.
Participate in quality assurance/quality control procedures.
Maintain detailed records of all testing activities.
Assist in the development of new protocols for efficient and accurate results.
Remain current on industry trends and advancements in molecular pathology technology.
Collaborate with clinicians, pathologists, and other laboratory personnel on research projects.

Skills and Competencies to Have

Working knowledge of histology and cytology techniques
Ability to operate, maintain and troubleshoot laboratory equipment
Proficiency in the use of laboratory information systems
Knowledge of relevant regulations and safety protocols
Ability to accurately interpret laboratory test results
Proficiency in performing molecular pathology procedures
Knowledge of clinical laboratory chemistry and hematology
Ability to collect, process and store specimens according to established protocols
Ability to perform quality control and preventive maintenance procedures
Ability to work independently and as part of a team
Excellent communication, problem-solving, and organizational skills
Attention to detail and accuracy

Molecular Pathology Technologists play an important role in the diagnosis of a wide range of diseases. Their ability to analyze and process complex molecular data is key to accurately detecting genetic and infectious diseases. As such, the most important skill for a Molecular Pathology Technologist is to have an extensive knowledge of the fundamentals of molecular biology, genetics and biochemistry.

This knowledge is essential for understanding the underlying processes in the various lab tests used for diagnosis. a Molecular Pathology Technologist must also have excellent laboratory skills in order to accurately perform tests, use lab equipment and troubleshoot any issues that may arise. Furthermore, having good communication and interpersonal skills is also important since they may need to interact with other healthcare professionals, patients, and their families.

With the right combination of knowledge, skills, and experience, a Molecular Pathology Technologist can make a significant contribution to medical research and diagnosis.

Microscopy Technician, Histology Processing Technician, and Cytotechnologist Supervisor are related jobs you may like.

Frequent Interview Questions

What experience do you have working as a Molecular Pathology Technologist?
What methods do you use to ensure accuracy and completeness of lab results?
How do you stay up to date on molecular pathology technology and techniques?
How would you handle a situation where the results of a molecular test are inconclusive?
What challenges have you faced when working with molecular pathology equipment?
Describe a time when you had to troubleshoot a problem with molecular pathology equipment.
How do you ensure the safety of specimens and equipment in the lab?
How would you prioritize tasks in a high-pressure environment?
What strategies have you used to increase efficiency in the lab?
Describe your experience working with a team of scientists on a molecular pathology project.

Common Tools in Industry

PCR (Polymerase Chain Reaction). a laboratory technique used to amplify target sequences of DNA or RNA. (eg: PCR can be used to detect the presence of a specific gene in a sample. )
Gel Electrophoresis. a laboratory technique used to separate molecules by size and charge. (eg: Gel electrophoresis can be used to separate DNA fragments of different sizes. )
Automated Nucleic Acid Extractor. a robotic instrument used to extract nucleic acid from a sample. (eg: An automated nucleic acid extractor can be used to isolate DNA from a patient sample. )
Mass Spectrometry. an analytical technique that measures the mass-to-charge ratio of ions in a sample. (eg: Mass spectrometry can be used to identify proteins in a sample. )
DNA Sequencing. a process that determines the nucleotide sequence of a DNA molecule. (eg: DNA sequencing can be used to study the genetic mutations present in a sample. )
Flow Cytometry. a technique used to measure physical and chemical characteristics of cells in a sample. (eg: Flow cytometry can be used to measure the expression of proteins on the cell surface. )

Professional Organizations to Know

American Society for Clinical Pathology (ASCP)
Association for Molecular Pathology (AMP)
European Society for Molecular Diagnostics (ESMD)
The American Board of Medical Genetics and Genomics (ABMGG)
American Association for Clinical Chemistry (AACC)
American Society for Histocompatibility and Immunogenetics (ASHI)
International Federation of Clinical Chemistry and Laboratory Medicine (IFCC)
American Board of Bioanalysis (ABB)
American Academy of Clinical Chemistry (AACC)
American Society for Investigative Pathology (ASIP)

We also have Histology Technical Supervisor, Specimen Receptionist, and Histopathologist jobs reports.

Common Important Terms

Next-Generation Sequencing (NGS) - A technology used to sequence DNA or RNA in a high-throughput manner, allowing for the rapid and accurate analysis of large chunks of genetic information.
PCR (Polymerase Chain Reaction) - A technique used to amplify a single or few copies of a piece of DNA to generate thousands to millions of copies of a particular DNA sequence.
Sanger Sequencing - A type of DNA sequencing method developed by Fred Sanger in 1977, that is based on the selective incorporation of chain-terminating dideoxynucleotides by DNA polymerase during in vitro DNA replication.
Gene Expression Analysis - A technique used to measure the amount of a particular gene that is expressed in an organism, tissue, or cell.
Bioinformatics - The use of computer science and data analysis techniques to understand biological data such as DNA sequences, protein sequences, and gene expression data.
Immunohistochemistry (IHC) - A technique used to detect the presence of specific proteins in tissue specimens.
Flow Cytometry - A technique used to measure the physical and chemical characteristics of cells or particles suspended in a fluid.
Digital PCR (dPCR) - A technique used to analyze DNA or RNA that is more accurate and sensitive than traditional PCR methods.
Genotyping - The process of determining the genotype of an individual by analyzing their DNA sequence.

Frequently Asked Questions

Q1: What is a Molecular Pathology Technologist? A1: A Molecular Pathology Technologist is a medical laboratory professional who specializes in molecular diagnostics techniques, such as DNA and RNA analysis, to diagnose and treat diseases. Q2: What skills are required for a Molecular Pathology Technologist? A2: Molecular Pathology Technologists must have strong laboratory skills, such as sterile technique and safety procedures, as well as advanced knowledge of molecular biology and biochemistry. They must also have excellent problem-solving and communication skills. Q3: How many years of education is required to become a Molecular Pathology Technologist? A3: To become a Molecular Pathology Technologist, individuals typically need to have a bachelor's degree in a related field, such as molecular biology or biochemistry, and at least one year of experience in a clinical laboratory setting. Q4: What are the job duties of a Molecular Pathology Technologist? A4: The job duties of a Molecular Pathology Technologist include preparing and analyzing samples, using instruments to detect genetic mutations, developing test protocols, documenting results, and communicating findings to physicians and other healthcare professionals. Q5: What is the average salary of a Molecular Pathology Technologist? A5: The average salary of a Molecular Pathology Technologist is $71,000 per year.

Web Resources

Molecular Pathology | University of Pennsylvania | Pathology and ... pathology.med.upenn.edu
Home - Molecular Pathology Division | Johns Hopkins Pathology pathology.jhu.edu
Master of Science in Molecular Pathology | Texas Tech www.ttuhsc.edu